2C-B is metabolized by the monoamine oxidases (MAOs) A and B, so it likely poses a risk for people on MAO inhibitors (MAOIs).1920 These include some types of antidepressants, as well as ayahuasca. Though there isn’t much research into the psychological or physiological effects of 2C-B, there is plenty of anecdotal evidence that suggests it could be beneficial for both therapeutic purposes and personal/spiritual development. Shulgin himself recommended the use of this compound in therapy and gave it to a handful of psychologists to use with patients. He also suggested that the drug could be used in conjunction with MDMA to ease the comedown and solidify any revelations brought on by the experience. The Global Survey suggests that its sales and purchase have been increasing over the past five years, along with other notable drugs like ketamine and DMT. Many of these dealers were found to be selling 2C-B while confusing it with MDMA, while others were deliberately trying to pass off the former as the latter to the customers to earn more profits.

Commonly Reported Effects of 2C-B

The drug is commonly used as a party drug as it provides stimulant effects similar to cocaine as well as hallucinatory effects similar to MDMA. Learn about 3-MMC, a synthetic cathinone, its effects, risks, legal status, and how to approach harm reduction. Ketamine Resources, Studies, and Trusted InformationCurious to learn more about ketamine? This guide includes comprehensive ketamine resources containing books, studies and more. Guide to Machine Elves and Other DMT EntitiesThis guide discusses machine elves, clockwork elves, and other common DMT entities that people experience during a DMT trip. New Johns Hopkins StudyJohns Hopkins University School of Medicines has just published a new study on psychoactive effects of psilocybin.

In order to understand the implications of ayahuasca treatment, we need to understand how PTSD develops. The Therapeutic Value of AyahuascaMy best description of the impact of ayahuasca is that it’s a rocket boost to psychospiritual growth and unfolding, my professional specialty during 2c-b effects my thirty-five years of private practice. Microdosing DMT & Common Dosages ExplainedMicrodosing, though imperceivable, is showing to have many health benefits–here is everything you want to know about microdosing DMT. Beating Addiction with DMTPsychedelics have been studied for their help overcoming addiction.

2. Impact of 2C-I and 25I-NBOMe on C. elegans Development over Time

Exclusion criteria were history of any serious medical or mental disorder including drug dependence (except for nicotine), use of chronic medication, and serious adverse reactions with 2C-B. Regardless of the prevailing narrative among users, then, 2C-B does come with its negatives. Like MDMA, the drug affects heart rate and the central nervous system, and people occasionally experience headaches after large doses.

• 2C-B can also be vaporized — but this isn’t a common way of using it, and the long-term health effects of taking 2C-B this way aren’t well understood.
• For that reason, this guide is designed to ensure the safety of those who decide to use the substance.
• The hallucinogenic properties of 2C-B are known for producing intense visual and auditory hallucinations, emotional euphoria, and sensory distortions, as well as dissociations similar to ketamine.

Anecdotal reports on sites like Reddit, as well as through our own surveys, suggest some people prefer to take large doses of the drug (over 50 mg) — without experiencing any severe side effects. There are no reported overdose deaths from people who took 2C-B. Additionally, the few clinical trials that are available involving 2C-B have all reported the drug had little to no side effects and that the drug had a high level of safety. 2C-B is often used as an alternative to MDMA (ecstasy) at concerts, music festivals, or parties.

Conceptual thinking, introspective insights, and spiritual ideation are also common—especially when alone. 2C-B has been used as an aphrodisiac, entheogen, dance drug, ecstasy adulterant, and psychotherapeutic aid. However, it has yet to gain widespread acceptance and it has been banned in most countries since the mid-1990s.

Tripping on This Forgotten Psychedelic

• In the United Kingdom, 2C-B is a Class A drug — which implies the drug poses a significant danger to public health and brings the most severe punishments to those caught in possession of the drug.
• All 2C- substances contain methoxy groups on the 2 and 5 positions of a benzene ring of its chemical structure.
• One of the main benefits of 2C-B over MDMA is that users usually don’t experience difficulty falling asleep after the experience.
• Some people argue the euphoria induced by 2C-B isn’t “earned.” This means you don’t actually have to do anything to feel the euphoria; it’s merely a byproduct of the substance itself.

The golden age of psychedelic research, the 1950s and ’60s, saw a huge number of clinical studies being conducted. However, the infamous ban on psychedelics in 1971 shut down the burgeoning field of psychedelic research. As 2C-B wasn’t even created by this time, this left no room for the drug to be officially investigated as a therapeutic substance. Changes in vital signs/physiological outcomes are shown in Table 1 and Figure 1A. Maximum effects (Emax) were +19 mmHg, +13 mmHg, and +13 bpm, respectively. Compared to baseline values, statistically significant differences were detected for SBP from 1 to 4 h and from 1 to 3 h for DBP and HR.

Though part of the same family of compounds, 2C-B isn’t the same as 2C-P, the more dangerous drug implicated in the death of Louella Fletcher-Michie at Bestival in 2017. Unlike 2C-B, 2C-P has a history of overdoses dating back to the early-90s – although Fletcher-Michie was the first recorded death – and today is sold by just one darknet dealer. However, it’s still available on the regular internet as a research chemical from legal sites aimed, in theory, at scientists.

Yes, I Bought an Atari Classic Controller Just To Play ‘Yars Revenge’. No, I Don’t Regret It in the Slightest

2C drugs are fairly unique as they exist primarily as a hallucinogen but also produce effects similar to stimulants. The hallucinogenic properties of 2C-B are known for producing intense visual and auditory hallucinations, emotional euphoria, and sensory distortions, as well as dissociations similar to ketamine. Additionally, the stimulant properties can cause alertness, increased sociability, and the ability to stay awake longer, like cocaine or MDMA. Despite how popular this substance is, there are no clinical trials or even toxicology studies to date. The only data we have available comes from anecdotal reports, observational studies, and in vitro research. If you want to contribute your experience to improve our understanding of 2C-B or other psychedelics, consider filling out one or more of our psychedelic surveys and sharing your experience.

Some users have also reported experiencing muscle clenching and claustrophobia while on 2C-B. Others experienced negative emotions like grief, anger, fear and physical symptoms like diarrhoea, gas, nausea, and vomiting. 2C-B is also known to cause introspective thoughts in addition to experiencing empathy and a softened ego. In this article, we explore the origins, effects, and dangers of 2C-B, while discussing its growing popularity as a designer drug. By understanding the nature of this substance, we can better recognize its potential risks and the implications it holds for mental health and addiction treatment.

What do 2C drugs look, smell, and taste like?

The comedown on 2C-B is very slow and gradual — which is considered one of the advantages of this substance. Most amphetamines or other stimulants tend to produce a rapid comedown — which can make users feel depressed. Of our respondents, only 7% reported any negative impact the following morning after using doses lower than 35 mg of 2C-B.

2C drugs come in multiple forms including 2C-E, 2C-I, 2CT-7, and 2CB which is the most commonly used version available today. Thus, it is difficult to talk about its potential benefits and risks in definitive terms. 2C-B will stay in your oral fluid for hours.With that said, the substance is extremely hard to detect and standard drug tests are not capable of that. In case you are not ready to face your inner demons yet, there are a few ways to end a bad trip.One possible way is to put on music that is familiar to you.

Users typically ingest 2C-B as they begin to come down from the MDMA. About an hour later, one reenters the experience with the enhanced visuals of the psychedelic. 2C-B and other 2C typically come as a white powder or in gel caps. One can dissolve the powder in a liquid or “bomb” it, which means to wrap the power in cigarette paper and swallow it. The reasons for its use are experimental, recreational, spiritual, and in some cases therapeutic. You can microdose with 2C-B but drugs like LSD, psilocybin, and ibogaine are more suited for this.

At high enough doses, 2C-B produces visual effects, which often include geometric patterns, after-images and tracers, facial distortions, environmental drifting (e.g. melting or flowing surfaces), and enhanced or shifting colors. Closed-eye visuals are often richer, with profound fantasy imagery. At higher doses, these hallucinations can become unpleasant, ugly, or even frightening. Remember to avoid using 2C-B in public places and especially before taking part in any risky activity, such as driving. This is because the drug can negatively impact visual perception and attention span. 2C-B can also negatively affect the gastrointestinal system, leading to issues such as diarrhoea, nausea, stomach cramps, and vomiting.

With that said, there is a serious lack of research available on the safety of 2C-B. Due to the heavily restricted status of this substance, it’s unlikely we’re going to see this research anytime in the near future. The 35 mg dose is a potent psychedelic — and very high doses (50 mg or more) are profoundly psychedelic and have even been known to induce out-of-body experiences.

In Third Wave’s Ultimate Guide to Safely Sourcing Psychedelics, you will discover an astonishing menu of psychedelic medicines……and how to source them without legal risk. By signing up to the Psychedelic Spotlight newsletter you agree to receive electronic communications from Psychedelic Spotlight that may sometimes include advertisements or sponsored content. Psychedelic Spotlight is your reliable source for the latest stories in the emerging psychedelics industry, covering breakthrough discoveries, investor news and cultural reform. A single 25mg dose of psilocybin paired with psychological support has resulted in 57% of patients.